The upcoming NFL face-off between the New Orleans Saints and the Los Angeles Rams is scheduled to take place at SoFi Stadium in Inglewood on November 2, 2025, at 4:05 PM. This matchup pits the struggling Saints, currently 4th in their division and 16th in the conference with a 0-4 record, against a stronger Rams team ranked 3rd in their division and 6th in the conference with a 3-1 record. The Rams have outscored their opponents 100 to 81 while the Saints have struggled, scoring 66 points to their opponents’ 121.

In their last game, the Saints were defeated 33-10 by DEN at Caesars Superdome despite gaining 271 total yards. The Rams secured a victory over LV with a final score of 20-15, accumulating 259 total yards. Quarterback Spencer Rattler of the Saints and Matthew Stafford of the Rams are set to lead their teams once again. Last week, Rattler passed for 172 yards and Stafford for 154 yards, setting the stage for an intriguing quarterback duel.

For betting enthusiasts, the game presents some fascinating odds. The Los Angeles Rams are favored with a point spread of -9.50, contrasting sharply with the Saints at 9.60. The total for the over/under is set at 44.70. When it comes to the moneyline, the Rams are priced at -457, indicating strong confidence in their victory, whereas the Saints stand at 352, suggesting a potential high reward for a risky bet. These odds reflect the current form and standing of both teams, offering insights for potential betting strategies.